97. Chemodivergent manganese-catalyzed C–H Activation: modular synthesis of fluorogenic probes

Nikolaos Kaplaneris, Jongwoo Son, Lorena Mendive-Tapia, Adelina Kopp, Nicole Barth, Isaac Maksso, Marc Vendrell,* Lutz Ackermann*

Nat. Commun. 2021, accepted


96. Photoactivatable metabolic warheads enable precise and safe ablation of target cells in vivo

Sam Benson, Fabio de Moliner, Antonio Fernandez, Erkin Kuru, Nicholas Asiimwe, Jun-Seok Lee, Lloyd Hamilton, Dirk Sieger, Isabel Ribeiro Bravo, Abigail Elliot, Yi Feng, Marc Vendrell*

Nat. Commun. 2021, 12, 2369, doi: 10.1038/s41467-021-22578

(Protected in patent WO 2020/187913)

95. A palette of minimally-tagged sucrose analogues for real-time Raman imaging of intracellular plant metabolism

Fabio de Moliner, Kirsten Knox, Doireann Gordon, Martin Lee, William J Tipping, Ailsa Geddis, Anke Reinders, John M Ward, Karl Oparka, Marc Vendrell*

Angew. Chem. Int. Ed. 2021, 60, 7637-7642, doi: 10.1002/anie.202016802

(Featured in Synfacts by Dirk Trauner and Anna C. Impastato)

94. A functional chemiluminescent probe for in vivo imaging of Natural Killer cell activity against tumours

Jamie Scott, Sara Gutkin, Ori Green, Emily J. Thompson, Takanori Kitamura, Doron Shabat, Marc Vendrell*

Angew. Chem. Int. Ed. 2021, 60, 5699-5703, doi: 10.1002/anie.202011429

(Featured as Hot paper)

93. Genotype-phenotype map of an RNA-ligand complex

Olga Puchta, Grzegorz Sobczyk, Vanessa Smer-Barreto, Hollie Ireland, Marc Vendrell, Diego A. Oyarzún, Janusz M. Bujnicki, Graeme Whyte, Grzegorz Kudla

BioRxiv 2020, doi: 10.1101/2020.12.17.423258

92. A fluorogenic cyclic peptide for imaging and quantification of drug-induced apoptosis

Nicole Barth, Ramon Subiros-Funosas, Lorena Mendive-Tapia, Rodger Duffin, Mario Shields, Jennifer Cartwright, Sónia Troeira Henriques, Jesus Sot, Felix Goñi, Rodolfo Lavilla, John Marwick, Sonja Vermeren, Adriano Rossi, Mikala Egeblad, Ian Dransfield, Marc Vendrell*

Nat. Commun. 2020, 11, 4027, doi: 10.1038/s41467-020-17772-7

(Apo-15 licensed to BioLegend and commercialised as Apotracker Green)

91. Fluorescent cyclic peptides for cell imaging

Lorena Mendive-Tapia, Jinling Wang, Marc Vendrell*

Pep. Sci. 2020, e24181, doi: 10.1002/pep2.24181


90. Fluorescent amino acids as versatile building blocks for chemical biology

Zhiming Cheng, Erkin Kuru, Amit Sachdeva, Marc Vendrell*

Nat. Rev. Chem. 2020, 4, 275-290, doi: 10.1038/s41570-020-0186-z

(Featured in Front cover)

89. Fluorogenic Trp(redBODIPY) cyclopeptide targeting keratin 1 for imaging of aggressive carcinomas

Ramon Subiros-Funosas, Vivian Cheuk Lam Ho, Nicole Barth, Lorena Mendive-Tapia, Morena Pappalardo, Xavier Barril, Ruoyu Ma, Chengbin Zhang, Bin-Zhi Qian, Miquel Sintes, Ouldouz Ghashghaei, Rodolfo Lavilla, Marc Vendrell*

Chem. Sci. 2020, 11, 1368-1374, doi: 10.1039/C9SC05558D

88. A fluorescent activatable AND-Gate chemokine CCL2 enables in vivo detection of metastasis-associated macrophages

Antonio Fernandez, Emily J. Thompson, Jeffrey W. Pollard, Takanori Kitamura, Marc Vendrell*

Angew. Chem. Int. Ed. 2019, 58, 16894-16898, doi: 10.1002/ange.201910955

(Featured in 87 news outlets, including Google News). Highest Altmetric Score out of all time in Angewandte Chemie.

87. Assessment of neutrophil apoptosis

Nicole D. Barth, Marc Vendrell, David A. Dorward, Adriano G. Rossi, Ian Dransfield

Neutrophil: Methods and Protocols (Eds: Mark T. Quinn, Frank DeLeo), Methods in Molecular Biology, 2087, pp. 167-190 (2020), Springer Nature, doi: 10.1007/978-1-0716-0154-9_13

86. Large expert-curated database for benchmarking document similarity detection in biomedical literature search

Peter Brown, RELISH Consortium, Yaoqi Zhou

Database 2019, 1-66, doi: 10.1093/database/baz085

85. BODIPY-labeled cyclobutanes by secondary C(sp3)-H arylations for live-cell imaging

Matteo Virelli, Wei Wang, Rositha Kuniyil, Jun Wu, Giuseppe Zanoni, Antonio Fernandez, Jamie Scott, Marc Vendrell, Lutz Ackermann

Chem. Eur. J. 2019, 25, 12712-12718, doi: 10.1002/chem.201903461

(Featured as Hot Paper)


84. Natural product-inspired profluorophores for imaging NQO1 activity in tumour tissues

Zhi Ming Cheng, Wagner O. Valença, Gleiston G. Dias, Jamie Scott, Nicole D. Barth, Fabio de Moliner, Gabriela B. P. Souza, Richard J. Mellanby, Marc Vendrell*, Eufrânio N. da Silva Junior*

Bioorg. Med. Chem. 2019, 27, 3938-3946, doi: 10.1016/j.bmc.2019.07.017

(Featured in the special issue 'Chemical Immunology')

83. 3D bioprinting of mature bacterial biofilms for antimicrobial resistance drug testing

Evita Ning, Gareth Turnbull, Jon Clarke, Frederic Picard, Philip Riches, Marc Vendrell, Duncan Graham, Alastair Wark, Karen Faulds, Wenmiao Shu

Biofabrication 2019, 045018, doi: 10.1088/1758-5090/ab37a0

82. In vivo tumor visualization through MRI off-on switching of NaGdF4–CaCO3 nanoconjugates

Zhigao Yi, Zichao Luo, Nicole D. Barth, Xianfu Meng, Hong Liu, Wenbo Bu, Angelo All, Marc Vendrell, Xiaogang Liu

Adv. Mater. 2019, 1901851, doi: 10.1002/adma.201901851

81. Enhanced avidity from a multivalent fluorescent antimicrobial peptide enables pathogen detection in a human lung model

Ahsan Akram, Nicolaos Avlonitis, Emma Scholefield, Marc Vendrell, Neil McDonald, Tashfeen Aslam, Thomas H. Craven, Calum Gray, David Collie, Andrew Fisher, Paul A. Corris, Timothy Walsh, Christopher Haslett, Mark Bradley, Kevin Dhaliwal

Sci. Reports 2019, 9, 8422, doi: 10.1038/s41598-019-44804-0

80. A near-infrared probe for in vivo imaging of colorectal lesions in high-risk patients

Stephan Rogalla, Antonio Fernandez, Sanjiv S Gambhir, Marc Vendrell*

Gastroenterology 2019, 156, S376-S377, doi: 10.1016/S0016-5085(19)37785-6

79. SCOTfluors: small, conjugatable, orthogonal and tunable fluorophores for in vivo imaging of cell metabolism.

Sam Benson, Antonio Fernandez, Nicole Barth, Fabio de Moliner, Mathew Horrocks, C Simon Herrington, Jose Luis Abad, Antonio Delgado, Lisa Kelly, Ziyuan Chang, Yi Feng, Miyako Nishiura, Yuichiro Hori, Kazuya Kikuchi, Marc Vendrell*

Angew. Chem. Int. Ed. 2019, 58, 6911-6915, doi: 10.1002/anie.201900465

(Protected in patent WO 2020/187919)

(Featured as Hot paper and in Angewandte Chemie Press Room)

(Featured in Synfacts by Dirk Trauner and Katharina Hull)

(TOP downloaded article in 2018-2019 Angewandte Chemie)

(Featured in The Times, Daily Star, Metro, The Herald, The Scotsman, The Press and Journal, The Courier, www.ITV.com, www.thenational.scot, www.phys.org, www.news-medical.net, www.devdiscourse.com, www.newatlas.com, www.AOL.co.uk, www.IrishNews.com, www.belfasttelegraph.co.uk, www.BT.com, www.thetele.co.uk, www.breakingnews.ie, www.shropshirestar.com, www.jerseyeveningpost.com, www.eveningexpress.co.uk, www.irishexaminer.com, www.bionity.com, Yahoo News, UoE news, Express&Star, Business Standard, The Times India, Medindia, Newswise, www.bbc.co.uk, BBC World Service). Highest Altmetric Score out of all inputs of similar age in Angewandte Chemie.

78. Fluorescent peptides for imaging of fungal cells.

Can Zhao, Lorena Mendive-Tapia, Marc Vendrell*

Arch. Biochem. Biophys. 2019, 661, 187-195, doi: 10.1016/j.abb.2018.11.018

(Featured in special issue 'Peptides')

77. Fluorogenic peptides for the detection of programmed cell death.

Ramon Subiros-Funosas, Nicole Barth, Jesus Sot, Felix Goni, Lorena Mendive-Tapia, Rodolfo Lavilla, Rodger Duffin, Adriano Rossi, Ian Dransfield, Marc Vendrell*

J. Pep. Sci. 2018, 24, S66-S67

 76. Tricarbocyanine N-triazoles: the scaffold-of-choice for long-term near-infrared imaging of immune cells in vivo.

Richard Mellanby, Jamie Scott, Iris Mair, Antonio Fernandez, Louise Saul, Jochen Arlt, Monica Moral, Marc Vendrell*

Chem. Sci. 2018, 9, 7261-7270, doi: 10.1039/C8SC00900G

(Protected in patent WO 2020/020905)

(Featured in The Herald, The Scotsman, The Press and Journal, UoE News)

75. Quinone-derived π-extended phenazines as new fluorogenic probes for live-cell imaging of lipid droplets.

Fabio de Moliner, Aaron King, Gleiston G. Dias, Guilherme F. de Lima, Carlos A. de Simone, Eufrânio N. da Silva Júnior, Marc Vendrell*

Front. Chem. 2018, 6, 339, doi: 10.3389/fchem.2018.00339

74. A remote control for switching.

Marc Vendrell*

Nat. Chem. Biol. 2018, 14, 749-750, doi: 10.1038/s41589-018-0107-3

73. Multiple multicomponent reactions: unexplored substrates, selective processes and versatile chemotypes in biomedicine.

Ouldouz Ghashghaei, Samantha Caputo, Miquel Sintes, Marc Revés, Nicola Kielland, Carolina Estarellas, F. Javier Luque, Anna Aviñó, Ramón Eritja, Ana Serna-Gallego, José Antonio Marrugal-Lorenzo, Jerónimo Pachón, Javier Sánchez-Céspedes, Ryan Treadwell, Fabio de Moliner, Marc Vendrell, Rodolfo Lavilla

Chem. Eur. J. 2018, 24, 14513-14521, doi: 10.1002/chem.201802877

(Featured as Hot Paper)

72. Probing binding specificity of the sucrose transporter AtSUC2 with fluorescent coumarin glucosides.

Fabio de Moliner, Kirsten Knox, Anke Reinders, John Ward, Paul McLaughlin, Karl Oparka, Marc Vendrell*

J. Exp. Bot., 2018, 69, 2473-2482, doi: 10.1093/jxb/ery075

(Featured in Faculty of 1000)

71. A fluorescent activatable probe for imaging intracellular Mg2+.

Ryan Treadwell, Fabio de Moliner, Ramon Subiros-Funosas, Toby Hurd, Kirsten Knox, Marc Vendrell*

Org. Biomol. Chem., 2018, 239-244, doi: 10.1039/c7ob02965a

(Featured in "Chemosensors and Molecular Logic" theme collection)

70. Quinone-based fluorophores for imaging biological processes.

Gleiston G. Dias, Aaron King, Fabio de Moliner, Marc Vendrell,* Eufranio N. da Silva Junior*

Chem. Soc. Rev., 2018, 47, 12-27, doi: 10.1039/c7cs00553a

(Featured in the front cover of the 2018 Emerging Investigators Issue)

​69. Fluorophore-drug conjugates to unravel the mechanisms of action of therapeutic assets.

Antonio Fernandez, Marc Vendrell*

Biochemistry, 2018, 57, 175-176, doi:10.1021/acs.biochem.7b00889

(Featured in the special issue 'Future of Biochemistry')

68. The 'phagocytic synapse' and clearance of apoptotic cells.

Nicole Barth, John A. Marwick, Marc Vendrell, Adriano Rossi, Ian Dransfield

Frontiers Immunol., 2017, 8, 1708, doi: 10.3389/fimmu.2017.01708

​67. Chemical modulation of in vivo macrophage function with subpopulation-specific fluorescent prodrug conjugates.

Antonio Fernandez, Matthieu Vermeren, Duncan Humphries, Ramon Subiros-Funosas, Nicole Barth, Lara Campana, Alison MacKinnon, Yi Feng, Marc Vendrell*

ACS Cent. Sci., 2017, 3, 995-1005, doi:10.1021/acscentsci.7b00262

​​66. On the synthesis of quinone-based BODIPY hybrids: new insights on antitumor activity and mechanism of action in cancer cells.

Talita B. Gontijo, Rossimiriam P. de Freitas, Flavio S. Emery, Leandro F. Pedrosa, José B. Vieira Neto, Bruno C. Cavalcanti, Claudia Pessoa, Aaron King, Fabio de Moliner, Marc Vendrell*, Eufranio N. da Silva Júnior*

Bioorg. Med. Chem. Lett., 2017, 27, 4446-4456, doi:10.1016/j.bmcl.2017.08.007

65. Preparation of a Trp-BODIPY fluorogenic amino acid to label peptides for enhanced live-cell imaging.

Lorena Mendive-Tapia, Ramon Subiros-Funosas, Can Zhao, Fernando Albericio, Nick D. Read, Rodolfo Lavilla, Marc Vendrell*

Nat. Protoc., 2017, 12, 1588–1619, doi:10.1038/nprot.2017.048

64. A Trp-BODIPY cyclic peptide for fluorescence labelling of apoptotic bodies.

Ramon Subiros-FunosasLorena Mendive-TapiaJesus SotJohn PoundNicole BarthYaiza VarelaFelix Goñi,   Margaret PatersonChristopher GregoryFernando AlbericioIan DransfieldRodolfo Lavilla, Marc Vendrell*

Chem. Commun., 2017, 53, 945-948, doi: 10.1039/C6CC07879F

(Featured in "Biological Optical Imaging" theme collection)

63. Optical windows for imaging the metastatic tumour microenvironment in vivo.

Takanori Kitamura, Jeffrey W. Pollard, Marc Vendrell*

Trends Biotechnol., 2017, 35, 5-8, doi:10.1016/j.tibtech.2016.05.001

62. Modern synthetic avenues for the preparation of functional fluorophores.

Fabio De Moliner, Nicola Kielland, Rodolfo Lavilla, Marc Vendrell*

Angew. Chem. Int. Ed.., 2017, 56, 3758–3769, doi: 10.1002/anie.201609394 and 10.1002/ange.201609394

61. Selective detection of apoptotic vesicles with fluorescent Trp-BODIPY labelled cyclic peptides.

Ramon Subiros-Funosas, Lorena Mendive-Tapia, John Pound, Jesus Sot, Felix M. Goni, Fernando Albericio, Rodolfo Lavilla, Marc Vendrell*

J. Pep. Sci., 2016, 22, S216.

60. Trp-BODIPY fluorogenic amino acids for minimally invasive labelling of peptides and enhanced live cell fluorescence imaging.

Lorena Mendive-Tapia, Ramon Subiros-Funosas, Can Zhao, Ahsan R. Akram, Fernando Albericio, Nick D. Read, Rodolfo Lavilla, Marc Vendrell*

J. Pep. Sci., 2016, 22, S46.

​​59. Searching for the optimal fluorophore to label antimicrobial peptides.

Can Zhao, Antonio Fernandez, Nicolaos Avlonitis, Greetje Vande Velde, Mark Bradley, Nick D. Read, Marc Vendrell*

ACS Comb. Sci., 2016, 18, 689–696, doi: 10.1021/acscombsci.6b00081

(Featured in front cover)

58. Electrophilic, activation-free fluorogenic reagent for labeling bioactive amines.

Miquel Sintes, Fabio De Moliner, David Caballero-Lima, David W. Denning, Nick D. Read, Nicola Kielland,* Marc Vendrell,* Rodolfo Lavilla*

Bioconjugate Chem., 2016, 27, 1430-1434, doi:10.1021/acs.bioconjchem.6b00245

57. Editorial (Thematic Issue: Combinatorial Fluorophores for Live Cell Imaging).

Marc Vendrell*

Comb. Chem. High Throughput Screen., 2016, 19, 346, doi: 10.2174/138620731905160510213909

​56. Red-​fluorescent activatable probes for the detection of hydrogen peroxide in living cells.

Claudia Garcia-Guzman, Antonio Fernandez, Nicolaos Avlonitis, Mark Bradley, Marc Vendrell*

Comb. Chem. High Throughput Screen., 2016, 19, 353-361, doi: 10.2174/1386207319666160408151313.

(Featured in front cover)

55. A highly selective fluorogenic probe for the detection and in vivo imaging of Cu/Zn superoxide dismutase.

Liyun Zhang, Jun Cheng Er, Hao Jiang, Xin Li, Zhaofeng Luo, Thomas Ramezani, Yi Feng, Mui Kee Tang, Young-Tae Chang, Marc Vendrell*

Chem. Commun., 2016, 52, 9093-9096, doi: 10.1039/C6CC00095A.

(Featured in "Chem Comm Emerging Investigators Issue 2016")

54. Smart fluorescent probes for imaging macrophage activity.

Antonio Fernandez, Marc Vendrell*

Chem. Soc. Rev., 2016, 45, 1182-1196, doi: 10.1039/C5CS00567A

(Featured in back cover)

53. Spacer-free BODIPY fluorogens in antimicrobial peptides for direct imaging of fungal infection in human tissue.

Lorena Mendive-Tapia, Can Zhao, Ahsan R. Akram, Sara Preciado, Fernando Albericio, Martin Lee, Alan Serrels, Nicola Kielland, Nick D. Read, Rodolfo Lavilla, Marc Vendrell*

Nat. Commun., 2016, 7, 10940-10948, doi: 10.1038/ncomms10940.

(Protected in patent WO 2016/207626)

(Featured in The Scotsman, UoE News, www.phys.org, Science Daily, www.electronicspecifier.com, www.myinforms.com, www.esciencenews.com, www.sciencenewsline.com, www.news.google.ca, www.greencity.edu.my, www.inomics.com, www.physnews.com, www.nationwidenewsbulletin.com, www.primenewscenter.com, www.technewscoverage.com, www.primetimereports.com, www.labmanager.com, www.jerseytribune.com, www.webnews.com, www.scicasts.com, www.diseasesresearchgroup.xonl.de, www.pdiinet.com, www.sci24h.com, www.bioportfolio.com)

52. Structural modifications of the antimicrobial peptide ubiquicidin for pulmonary imaging of bacteria in the alveolar space.

Ahsan R. Akram, Nicolaos Avlonitis, Thomas Craven, Marc Vendrell, Neil McDonald, Emma Scholefield, Andrew Fisher, Paul Corris, Chris Haslett, Mark Bradley, Kevin Dhaliwal.

The Lancet, 2016, 387, S17, doi: 10.1016/S0140-6736(16)00404-9

51. Optically detectable antimicrobial peptides enable the immediate detection of bacteria and fungi in the lung.

Ahsan R. Akram, Nicolaos Avlonitis, Marc Vendrell, Sunay Chankeshwara, Neil McDonald, Tashfeen Aslam, Emma Scholefield, Tim Walsh, Chris Haslett, Mark Bradley, Kevin Dhaliwal.

Thorax 2015, 70, A2–A3, doi: 10.1136/thoraxjnl-2015-207770.4.

50. Multispectral phloem-mobile probes - properties and applications.

Michael Knoblauch, Marc Vendrell, Erica de Leau, Andrea Paterlini, Kirsten Knox, Tim J Ross-Elliott, Anke Reinders, Stephen A. Brockman, John Ward, Karl Oparka

Plant Physiol., 2015, 167, 1211-1220, doi:10.1104/pp.114.255414

(Featured in Faculty of 1000)

49. A solid-phase combinatorial approach for indoloquinolizidine-peptides with high affinity at D1 and D2 dopamine receptors.

Anabel Molero, Marc Vendrell,* Jordi Bonaventura, Julian Zachmann, Laura López, Leonardo Pardo, Carme Lluis, Antoni Cortés, Fernando Albericio, Vicent Casadó, Miriam Royo*

Eur. J. Med. Chem., 2015, 97, 173-180, doi:10.1016/j.ejmech.2015.04.052

48. A highly selective fluorescent probe for direct detection and isolation of mouse embryonic stem cells.

Yogeswari Chandran, Nam-Young Kang, Sung-Jin Park, Samira Husen Alamudi, Jun-Young Kim, Srikanta Sahu, Dongdong Su, Jungyeol Lee, Marc Vendrell,* Young-Tae Chang*

Bioorg. Med. Chem. Lett., 2015, 25, 4862-4865, doi:10.1016/j.bmcl.2015.06.037

47. Mechanistic elements and critical factors of cellular reprogramming revealed by stepwise global gene expression analyses.

Sung-Jin Park, Hock Chuan Yeo, Nam-Young Kang, Hanjo Kim, Joyce Lin, Hyung-Ho Ha, Marc Vendrell, Jun-Seok Lee, Yogeswari Chandran, Dong-Yup Lee, Seong-Wook Yun, Young-Tae Chang.

Stem Cell Res., 2014, 12, 730-741, doi:10.1016/j.scr.2014.03.002

46. Multicomponent reactions for de novo synthesis of BODIPY probes: in vivo imaging of phagocytic macrophages.

Ana M. Vazquez-Romero, Nicola Kielland, Maria J. Arevalo, Sara Preciado, Richard J Mellanby, Yi Feng, Rodolfo Lavilla, Marc Vendrell*

J. Am. Chem. Soc., 2013, 135, 16018-16021, doi:10.1021/ja408093p

(Featured in UB News)

45. Fluorescent dye cocktail for multiplex drug-site mapping on human serum albumin.

Jun Cheng Er, Marc Vendrell, Mui Kee Tang, Duanting Zhai, Young-Tae Chang

ACS Comb. Sci., 2013, 15 , 452–457, doi:10.1021/co400060b  

(Featured in front cover)

44. MegaStokes BODIPY-triazoles as environmentally-sensitive turn-on fluorescent dyes.

Jun Cheng Er, Mui Kee Tang, Chee Geng Chia, Huimin Liew, Marc Vendrell*, Young-Tae Chang*

Chem. Sci., 2013, 4, 2168-2176, doi:10.1039/C3SC22166K 

43. Surface enhanced Raman scattering in cancer detection and imaging.

Marc Vendrell*, Kaustabh Kumar Maiti, Kevin Dhaliwal, Young-Tae Chang.

Trends Biotechnol., 2013, 31, 249-257, doi:10.1016/j.tibtech.2013.01.013

(Selected within the Top 25 Hottest Articles in 2013).

42. A fluorescent screening platform for the rapid evaluation of chemicals in reprogramming.

Marc Vendrell, Sung-Jin Park, Yogeswari Chandran, Ken Chi-Lik Lee, Hyung-Ho Ha, Nam-Young Kang, Seong-Wook Yun, Young-Tae Chang

Stem Cell Res., 2012, 9, 185-191, doi:10.1016/j.scr.2012.06.006

41. Combinatorial Strategies in fluorescent probe development.

Marc Vendrell*, Duanting Zhai, Jun Cheng Er, Young-Tae Chang*

Chem. Rev., 2012, 112, 4391-4420, doi:10.1021/cr200355j

(Within the most read articles from Chemical Reviews in 2012)

40. Combinatorial solid-phase synthesis of 4,6-diaryl and 4-aryl, 6-alkyl-1,3,5-triazines and their application to efficient biofuel production.

Jaoon Y.H. Kim, Jae Wook Lee, Woo Sirl Lee, Hyung-Ho Ha, Marc Vendrell, Jacqueline T. Bork, Youngsook Lee, Young-Tae Chang

ACS Comb. Sci., 2012, 14, 395-398, doi:10.1021/co300007a

39. Imaging histamine in live basophils and macrophages with a fluorescent mesoionic acid fluoride.

Nicola Kielland, Marc Vendrell, Rodolfo Lavilla, Young-Tae Chang

Chem. Commun., 2012, 48, 7401-7403, doi:10.1039/C2CC32292G

38. Multiplex targeted in vivo detection of cancer using sensitive near-infrared SERS nanotags.

Kaustabh Kumar Maiti, U. S. Dinish, Animesh Samanta, Marc Vendrell, Kiat-Seng Soh, Sung Jin Park, Malini Olivo, Young-Tae Chang

Nano Today, 2012, 7, 85-93, doi:10.1016/j.nantod.2012.02.008

37. Synthesis of a novel BODIPY library and its application in the discovery of a fructose sensor.

Duanting Zhai, Sung-Chan Lee, Marc Vendrell, Lai Peng Leong, Young-Tae Chang

ACS Comb. Sci., 2012, 14, 81-84, doi:10.1021/co200136b

(Within the most read articles from ACS Comb. Sci. in 2012)

36. Intracellular glutathione detection using MnO2-nanosheet-modified upconversion nanoparticles.

Renren Deng, Xiaoji Xie, Marc Vendrell, Young-Tae Chang, Xiaogang Liu

J. Am. Chem. Soc., 2011, 133, 20168-20171, doi:10.1021/ja2100774

35. Diversity-oriented optical imaging probe development.

Jun-Seok Lee, Marc Vendrell, Young-Tae Chang

Curr. Opin. Chem. Biol., 2011, 15, 760-767, doi:10.1016/j.cbpa.2011.10.007

34. Solid-phase synthesis of BODIPY Dyes and development of an immunoglobulin fluorescent sensor.

Marc Vendrell, Gaddamanugu Gopi Krishna, Krishna Kanta Ghosh, Duanting Zhai, Jun-Seok Lee, Qing Zhu, Yin Hoe Yau, Susana Geifman Shochat, Hyori Kim, Junho Chung, Young-Tae Chang

Chem. Commun., 2011, 47, 8424-8426, doi:10.1039/C1CC11774B

33. Combinatorial solid-phase synthesis of 6-aryl-1,3,5-triazines via Suzuki coupling.

Jae Wook Lee, Hyung-Ho Ha, Marc Vendrell, Jacqueline T. Bork, Young-Tae Chang

Aust. J. Chem., 2011, 64, 540-544, doi:10.1071/CH11034

32. Synthesis and characterization of a cell-permeable near-infrared fluorescent deoxyglucose analogue for cancer cell imaging.

Marc Vendrell, Animesh Samanta, Seong-Wook Yun, Young-Tae Chang

Org. Biomol. Chem., 2011, 9, 4760-4762, doi:10.1039/C1OB05519D

31. Ultrasensitive near-infrared Raman reporters for SERS-based in vivo cancer imaging.

Animesh Samanta, Kaustabh Kumar Maiti, Kiat-Seng Soh,  Xiaojun Liao, Marc Vendrell, U.S. Dinish, Seong-Wook Yun, Ramaswamy Bhuvaneswari, Hyori Kim, Shashi Rautela, Malini Olivo, Junho Chung, Young-Tae Chang

Angew. Chem. Int. Ed. 2011, 50, 6089-6092, doi:10.1002/anie.201007841

(Featured in A*STAR Research)

30. A photostable near-IR protein labeling dye for in vivo imaging.

Animesh Samanta, Marc Vendrell, Seong-Wook Yun, Zhenping Guan, Qing-Hua Xu, Young-Tae Chang

Chem. Asian J.,  2011, 6, 1353-1357, doi:10.1002/asia.201100041

29. Accelerating fluorescent sensor discovery: unbiased screening of a diversity-oriented BODIPY library.

Jun-Seok Lee, Hyeong Kyu Kim, Suihan Feng, Marc Vendrell, Young-Tae Chang

Chem. Commun., 2011, 47, 2339-2341, doi:10.1039/C0CC04495D

28. Biotin ergopeptide probes for dopamine receptors.

Marc Vendrell, Anabel Molero, Sergio Gonzalez, Kamil Pérez-Capote, Carme Lluis, Peter J. McCormick, Rafael Franco, Antoni Cortés, Vicent Casadó, Fernando Albericio, Miriam Royo

J. Med. Chem., 2011, 54, 1080-1090, doi:10.1021/jm101566d

27. Multiplex cancer cell Detection by SERS nanotags with triphenylmethine and cyanine Raman reporters.

Kaustabh Kumar Maiti, Animesh Samanta, Marc Vendrell, Kiat-Seng Soh, Young-Tae Chang

Chem. Commun., 2011, 47, 3514-3516, doi:10.1039/C0CC05265E

26. Combinatorial search of sensors.

Marc Vendrell, Suihan Feng, Young-Tae Chang

Chemosensors: Principles, Strategies and Applications (Eds: Binghe Wang & Eric V. Anslyn), Wiley-WCH, pp 87-106 (2011), doi:10.1002/9781118019580.ch6

25. Solid-phase synthesis of dyes and their application as sensors and bioimaging probes.

Marc Vendrell, Hyung-Ho Ha, Sung Chan Lee, Young-Tae Chang

Solid-Phase Organic Synthesis: Concepts, Strategies, and Applications (Eds: Patrick Toy & Yulin Lam), Wiley-WCH, pp. 427-440 (2011), doi:10.1002/9781118141649.ch14

24. A hybrid indoloquinolizidine peptide as allosteric modulator of dopamine D1 receptors.

Aroa Soriano, Marc Vendrell, Sergio Gonzalez, Josefa Mallol, Fernando Albericio, Miriam Royo, Carmen Lluís, Enric I. Canela, Rafael Franco, Antoni Cortés, Vicent Casadó.

J. Pharmacol. Exp. Ther., 2010, 332, 876-885, doi:10.1124/jpet.109.158824

23. Diversity-oriented fluorescence library approaches for probe discovery and development.

Marc Vendrell, Jun-Seok Lee, Young-Tae Chang

Curr. Opin. Chem. Biol., 2010, 14, 383-389, doi:10.1016/j.cbpa.2010.02.020

22. A Fluorescent Rosamine Compound Selectively Stains Pluripotent Stem Cells.

Chang-Nim Im, Nam Young Kang, Hyung Ho Ha, Xuezhi Bi, Jae Jung Lee, Sung-Jin Park, Sang Yeon Lee, Marc Vendrell, Yun Kyung Kim, Jun-Seok Lee, Jun Li, Young-Hoon Ahn, Bo Feng, Huck-Hui Ng, Seong-Wook Yun, Young-Tae Chang

Angew. Chem. Int. Ed., 2010, 49, 7659-7662, doi:10.1002/anie.201002463

(Featured in Chemical & Engineering News and in A-STAR Research).

21. Development of photostable near-infrared cyanine dyes.

Animesh Samanta, Marc Vendrell, Rajkumar Das, Young-Tae Chang

Chem. Commun., 2010, 46, 7406-7408, doi:10.1039/C0CC02366C

(Featured in Chem Inform)

20. Indoloquinolizidine-peptide hybrids as multiple agonists for D1 and D2 dopamine receptors.

Marc Vendrell, Aroa Soriano, Vicent Casadó, José Luis Díaz, Rodolfo Lavilla, Enric I. Canela, Carme Lluis, Rafael Franco, Fernando Albericio, Miriam Royo

ChemMedChem, 2009, 4, 1514-1522, doi:10.1002/cmdc.200900149

19. Diversity-oriented fluorescence library approach for the discovery of sensors and probes.

Jun-Seok Lee, Yun Kyung Kim, Marc Vendrell, Young-Tae Chang

Mol. Biosyst., 2009, 5, 411-421, doi:10.1039/B821766C

(Featured in front cover)

18. Synthesis of a BODIPY library and its application to the development of live cell glucagon imaging probe.

Jun-Seok Lee, Nam-young Kang, Yun Kyung Kim, Hyeong Kyu Kim, Animesh Samanta, Suihan Feng, Marc Vendrell, Jung Hwan Park, Young-Tae Chang

J. Am. Chem. Soc., 2009, 131, 10077-10082, doi:10.1021/ja9011657

(Featured in A-STAR Research and in JACS Select #10: Supramolecular and Chemical Cascade Approaches to Molecular Sensing).

17. Novel ergopeptides as dual ligands for adenosine and dopamine receptors.

Marc Vendrell, Ester Angulo, Vicent Casadó, Carme Lluís, Rafael Franco, Fernando Albericio, Miriam Royo

J. Med. Chem., 2007, 50, 3062-3069, doi: 10.1021/jm060947x

16. Multiple ligands applied to dopamine and adenosine receptors.

Marc Vendrell, Ester Angulo, Aroa Soriano, Anabel Molero, Vicent Casadó, Carme Lluis, Rafael Franco, Sergi Ferre, Fernando Albericio, Miriam Royo.

Proceedings of the 5th Austrian-German-Hungarian-Italian-Polish-Slovenian Joint Meeting on Medicinal Chemistry. (Ed: Danijel Kikelj), 2007.

15. Multicomponent reactions with dihydroazines. Efficient synthesis of a diverse set of pyrido-fused tetrahydroquinolines.

Inés Carranco, José Luis Díaz, Óscar Jiménez, Marc Vendrell, Fernando Albericio, Miriam Royo, Rodolfo Lavilla

J. Comb. Chem., 2005, 7, 33-41, doi:10.1021/cc049877a

(Within most-accessed articles in J. Comb. Chem. for 2005; Featured in Chem Inform)

14. N-[Chloro(dimethylamino)methylene]-N-methylmethanaminium chloride (TMUCl Cl), the reagent of choice for the solid-phase synthesis of anilides.

Marc Vendrell, Rubén Ventura, Ariel Ewenson, Miriam Royo, Fernando Albericio

Tet. Lett., 2005, 46, 5383-5386, doi:10.1016/j.tetlet.2005.05.140

13. A re-evaluation on the use of Rink, BAL and PAL resins and linkers.

Francesc Yraola, Rubén Ventura, Marc Vendrell, Aina Colombo, Joan-Carles Fernández, Natalia de la Figuera, Dolors Fernández-Forner, Miriam Royo, Pilar Forns, Fernando Albericio

QSAR Comb. Sci., 2004, 23, 145-152, doi:10.1002/qsar.200420013

12. Minimalism applied to a hit to lead program.

Marc Vendrell, Rubén Ventura,  Fernando Albericio, Rosario González-Muñiz, Laura García de Diego, Cristina Carreño, Antonio Ferrer-Montiel, Miriam Royo.

Peptide Revolution: Genomics, Proteomics & Therapeutics. 18th American Peptide Symposium (Eds: Michael Chorev & Tomi K. Sawyer), 2003.

11. Is it possible to minimize the toxicity of a hit compound without reducing its activity?

Rubén Ventura, Marc Vendrell, Fernando Albericio, Rosario González-Muñiz, Laura García de Diego, Cristina Carreño, Antonio Ferrer-Montiel, Miriam Royo.

Peptide Revolution: Genomics, Proteomics & Therapeutics. 18th American Peptide Symposium (Eds: Michael Chorev & Tomi K. Sawyer), 2003.


10. Small molecule photosensitizers for photodynamic therapy.

Marc Vendrell, Sam Benson, Antonio Fernandez, Fabio de Moliner, Nicole Barth.

WO 2020/187913

9. Small tunable fluorophores for the detection and imaging of biomolecules.

Marc Vendrell, Sam Benson, Antonio Fernandez, Fabio de Moliner, Nicole Barth.

WO 2020/187919


8. Near-infrared chromophores, process of preparation and methods of use.

​Marc Vendrell, Antonio Fernandez, Richard Mellanby, Jamie Scott, Iris Mair, Claudia Garcia-Guzman, Baljean Dhillon, Pierre Bagnaninchi

WO 2020/020905

7. Molecular probes for detecting gram-negative bacteria in vitro and in vivo.

Mark Bradley, Annamaria Lillenkampf, Nicolaos Avlonitis, Marc Vendrell, Neil McDonald, Chris Haslett, Kev Dhaliwal, Tim Walsh

WO 2016/075483 (granted in USA, Japan, Canada, India)

6. Fluorescent polybranched probes for detecting bacteria and/or fungi in vitro and in vivo.

Mark Bradley, Annamaria Lillenkampf, Nicolaos Avlonitis, Marc Vendrell, Neil McDonald, Chris Haslett, Kev Dhaliwal, Tim Walsh

WO 2016/075484 (granted in USA, Japan, Canada, India)


5. Fluorogenic amino acid derivatives, process of preparation thereof and methods of use.

​Marc Vendrell, Ramon Subiros-Funosas, Rodolfo Lavilla, Lorena Mendive-Tapia, Fernando Albericio, Nick Read

WO 2016/207626

4. Megastokes amino-triazolyl-BODIPY compounds and applications to live neuron staining and human serum albumin FA1 drug site probing.

Young-Tae Chang, Jun Cheng Er, Cheryl Kit Mun Leong, Seong-Wook Yun, Marc Vendrell, Mui Kee Tang.

WO 2014/104975 (granted in China, USA, Japan, EU, Korea, Singapore)

3. Alkylamino BODIPY dyes as selective fluorescent probes for proteins and mouse embryonic stem cells.

Young-Tae Chang, Marc Vendrell, Duanting Zhai, Nam-Young Kang, Yogeswari Chandran.

WO 2012/173575 (granted in EU, USA)

2. New cyanine dye used for labeling biomolecule e.g. protein and peptide, detecting presence of target in sample and functionalizing nanoparticles in biosensor.

Young-Tae Chang, Animesh Samanta, Marc Vendrell, Nam-Young Kang, Kaustabh Kumar Maiti, Kiat-Seng Soh, U.S. Dinish, Malini Olivo, Sung Jin Park.

WO 2011/119114 (granted in EU)

1. Pyrrolopyrimidine derivatives as JAK3 inhibitors.

Jorge Solanas, Carmen Almansa, Robert Soliva, Montserrat Fontes, Marc Vendrell.

WO 2008/119792 (granted in China, Israel, Australia, Canada, Korea, Mexico, EU, India, Russia, USA)