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Fluorescence lifetime imaging signatures for early diagnosis of lung cancer, and its regulation through the adenosine pathways

Funding body:   UKRI

Grant value:     £2,158,103

Period:            2024-2028

Role:               co-I (PI: Ahsan Akram)

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Organic D-dots for imaging infectious diseases

Funding body:   EPSRC IAA

Grant value:     €59,935

Period:            2024-2025

Role:               co-PI (with Eli Zysman-Colman)

ERO Vendrell EPSRC Healthcare Tech FMWOf

Near infrared fluorescence in Wilms tumour organoids

Funding body:   Little Princess Trust

Grant value:      £274,866

Period:            2024-2026

Role:               co-I (PI: Max Pachl)

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Disruptive technologies for rapid detection of renal transplant rejection

Funding body:   ERC Proof of Concept Grant - EU Commission

Grant value:     €150,000

Period:            2024-2025

Role:               PI

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Measurement of granzyme B activity in renal transplant patients: a pilot feasibility study

Funding body:   Kidney Research UK

Grant value:     €39,627

Period:            2023-2024

Role:               co-I (PI: Steve Knight)

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IBDSense

Funding body:   Scottish Enterprise (Company Creation)

Grant value:     £199,760

Period:            2023-2024

Role:               PI

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Non-invasive technologies for diagnosis and monitoring of inflammatory bowel diseases

Funding body:   EIC Transition

Grant value:     €2,466,590

Period:            2022-2025

Role:               PI

Development of pH sensitive dyes for intracellular trafficking of ADCs

Funding body:   AbbVie

Grant value:     £274,000

Period:            2023-2024

Role:               PI

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Translational photonic fingerprinting

Funding body:   MRC

Grant value:     £398,477

Period:            2022-2023

Role:               co-I (PI: Kev Dhaliwal)

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IBDSense

Funding body:   Scottish Enterprise (High Growth Spin Out Opportunity Qualification)

Grant value:     £74,785

Period:            2022-2023

Role:               PI

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Metabolic photosensitizers for photodynamic therapy of brain cancer

Funding body:   ESPRC Healthcare Technologies

Grant value:     £750,172

Period:            2022-2025

Role:               PI

ERO Vendrell EPSRC Healthcare Tech FMWOf

Instantaneous point-of-care testing of tacrolimus concentrations within transplant patients

Funding body:   4MD - Heriott-Watt University

Grant value:     £80,060

Period:            2021-2022

Role:               co-I (PI: Richard Carter)

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Pathways to reducing the burden of corneal ulcer in India and beyond

Funding body:   UKRI

Grant value:     £1,874,632

Period:            2022-2026

Role:               co-I (PI: Beth Mills)

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Lead optimisation of metabolic photosensitizers for precise

resection of glioblastoma

Funding body:   MRC (Confidence in Concept)

Grant value:     £125,544

Period:            2021

Role:               PI

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Novel imaging biomarkers of T cell function to accelerate immunotherapies for pancreatic cancer

Funding body:   Medical Research Scotland

Grant value:     £121,993

Period:            2021-2025

Role:               PI

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Multimodal coherent Raman and two-photon fluorescence imaging as a discovery tool in bioscience

Funding body:   BBSRC

Grant value:     £303,121

Period:            2020-2021

Role:               co-I (PI: Val Brunton)

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High-precision tools for intraoperative brain cancer surgery

Funding body:   MRC (DTP in Precision Medicine)

Grant value:     £100,000

Period:            2020-2024

Role:               PI (with Paul Brennan and EM Imaging)

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Nanoparticle-based imaging and therapy of chronic pain in the

dorsal root ganglia

Funding body:   MSCA-ITN, EU Commission

Grant value:     €4,093,424

Period:            2020-2024

Role:               Project Partner (Coordinator: Percuros BV)

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Identifying therapeutic targets for retinitis pigmentosa by

defining photoreceptor cell death

Funding body:   Royal College of Surgeons Edinburgh

Grant value:     £60,000

Period:            2020-2021

Role:               co-I (PI: Roly Megaw)

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Disruptive fluorescent technologies for inflammatory bowel diseases

Funding body:   ERC Proof of Concept Grant - EU Commission

Grant value:     €150,000

Period:            2021-2022

Role:               PI

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Developing a decision-making kit for the personalised treatment of inflammatory bowel disease

Funding body:   MRC (DTP in Precision Medicine)

Grant value:     £105,000

Period:            2019-2023

Role:               PI (with Gwo-tzer Ho and Genentech)

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Fluorescent sensors for super-resolution microscopy to revolutionise the imaging of neurodegeneration

Funding body:   Sydney-Edinburgh Partnership Collaboration Awards

Grant value:     20,000 AUD

Period:            2019-2020

Role:               PI (co-PI: Margaret Sunde)

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Proactive monitoring of cancer as an alternative to surgery

Funding body:   MSCA-RISE, EU Commission

Grant value:     €2,484,000

Period:            2020-2024

Role:               Project Partner (Coordinator: Percuros BV)

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Novel applications in 19F magnetic resonance imaging

Funding body:   MSCA-ITN - EU Commission

Grant value:     €4,051,634

Period:            2020-2024

Role:               Project Partner (Coordinator: Leiden LUMC)

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Super-resolution microscopy probes for neurodegenerative disorders

Funding body:   EPSRC (CDT SOFI)

Grant value:     £80,000

Period:            2018-2022

Role:               co-I (PI: Mathew Horrocks)

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Single-molecule detection of protein aggregates under flow

Funding body:   Alzheimer's Research UK

Grant value:     £39,609

Period:            2018-2019

Role:               co-I (PI: Mathew Horrocks)

Novel fluorescent biomarkers of apoptosis in diseased tissues

 

Funding body:   WT-iTPA

Grant value:     £20,000

Period:            2018-2019

Role:               PI

Development of a fluorogenic platform for imaging second messenger ion flux in macrophages

 

Funding body:   EPSRC/MRC

Grant value:     £80,000

Period:            2018-2022

Role:               co-I (PI: Glenn Burley)

Through tissue imaging of bacterial infections using SESORS imaging

 

Funding body:   EPSRC/MRC

Grant value:     £90,000

Period:            2018-2022

Role:               co-I (PI: Karen Faulds)

Functional imaging probes for GLUT4 localisation

 

Funding body:   The Royal Society

Grant value:     £12,000

Period:            2018-2020

Role:               PI

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iCBMIc 2019

 

Funding body:   British Korean Society

Grant value:     £1,000

Period:            2018-2019

Role:               PI

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Dynamic Activatable Fluorophores

Funding body:   ERC Consolidator Grant - EU Commission

Grant value:     €1,986,650

Period:            2018-2023

Role:               PI

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A new chemical platform for the rational design of drug-immunotherapy combinations for the treatment of pancreatic cancer

 

Funding body:   Alfonso Martin Escudero Fundation

Grant value:     €70,000

Period:            2018-2020

Role:               PI

Nanosensors to measure phosphorylation potential

 

Grant value:      £25,000

Period:             2017

Role:                co-I (PI: Colin Campbell)

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The role of macrophage CD71 and iron metabolism in lung fibrosis

 

Funding body:   EPSRC/MRC

Grant value:     £80,000

Period:            2017-2021

Role:               co-I (PI: Nik Hirani)

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New chemical imaging probes for real-time detection of apoptosis and enhanced monitoring of inflammatory diseases

 

Funding body:   Royal Society Research Grant

Grant value:     £15,000

Period:            2016-2017

Role:               PI

Development of new chemokine-based probes for imaging metastasis-associated macrophages

 

Funding body:   Wellcome Trust-Institutional Strategic Support Fund

Grant value:     £44,950

Period:            2016-2017

Role:               co-I (PI: Takanori Kitamura)

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Fluorescent small molecule probes to investigate neutrophil function

 

Funding body:   EPSRC/MRC

Grant value:     £80,000

Period:            2016-2020

Role:               co-PI (with Ian Dransfileld)

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Smart theranostic agents for the tumour microenvironment

 

Funding body:   Marie Curie Individual Fellowship - EU Commission

Grant value:     €195,455

Period:            2017-2019

Role:               PI

Novel theranostic agents for enhanced diagnosis and minimally invasive therapy of cervical cancer

 

Funding body:   Medical Research Scotland

Grant value:     £107,677

Period:            2016-2020

Role:               PI (with EM Imaging)

Optical Coherence Tomography for imaging macrophages in cardiovascular disease

Funding body:   EPSRC-MRC

Grant value:     £80,000

Period:            2015-2019

Role:               co-I  (PI: Marc Dweck)

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Unraveling host-pathogen interactions in the pathogenesis of cryptococcosis using optical and in vivo imaging methods

 

Funding body:   Infect-ERA, EU Commission

Grant value:     €775,325

Period:            2015-2018

Role:               Project Partner (Coordinator: Uwe Himmelreich)

Novel fluorophores for imaging in vivo the tumour microenvironment

 

Funding body:   EPSRC-MRC-Scottish Funding Council

Grant value:     £85,000

Period:            2015-2019

Role:               PI 

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Development of phloem-mobile xenobiotics with enhanced transport properties

 

Funding body:   BBSRC Industrial Partnership Award

Grant value:     £981,291

Period:            2015-2019

Role:               PI (with Karl Oparka) 

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Specific fluorogenic peptides for imaging metastasis-associated macrophages

 

Funding body:   Marie Curie Individual Fellowship - EU Commission

Grant value:     €183,445

Period:            2015-2017

Role:               PI

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New chemical smartprobes for diagnosis, molecular characterisation and therapy of human cancer by optical molecular imaging

 

Funding body:   Alfonso Martin Escudero Fundation

Grant value:     €60,700

Period:            2015-2016

Role:               PI

SESORS imaging of bacterial infection using responsive enhanced Raman reporters

 

Funding body:   EPSRC/MRC

Grant value:     £82,000

Period:            2014-2018

Role:              co-I (PI: Karen Faulds)

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Activatable probes as smart diagnostic tools for microendoscopy imaging

 

Funding body:   Marie Curie Integration Grant, EU Commission

Grant value:     €100,000

Period:            2013-2017

Role:               PI

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Multiplexed fluorescent probes for in vivo imaging of reactive oxygen species in zebrafish inflammatory models

 

Funding body:   Wellcome Trust-Institutional Strategic Support Fund

Grant value:     £25,000

Period:            2014

Role:               PI

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Molecular probes to define the pulmonary macrophage response in rat and man

 

Funding body:   NC3R CRACK-IT

Grant value:     £98,639

Period:            2013-2014

Role:              co-PI (with Mark Bradley)

Developing near-infrared to visible up-conversion nanoparticles for three-dimensional in vivo cancer imaging

 

Funding body:   A*STAR, Singapore

Grant value:     966,000 SGD

Period:            2012-2015

Role:               co-I (PI: Xiaogang Liu)

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